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As a dual-agonist, it targets two different incretin hormone receptors: glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide (GIP)

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If additional glycemic control is needed after at least 4 weeks on the: 0.5 mg dosage, the dosage may be increased to 1 mg once weekly

Women should discontinue GLP-1 medications before conception or as soon as pregnancy is confirmed, with semaglutide requiring cessation at least 2 months before planned pregnancy

& Messens, J